ea0081ep104 | Adrenal and Cardiovascular Endocrinology | ECE2022
Yasuda Atsushi
, Seki Toshiro
, Kitajima Natsumi
, Seki Masami
, Kametani Yoshie
(Aims) Regulation of humoral immunity is important to develop vaccines for infectious disease and cancer. However, human and mouse humoral immune systems contain different molecular mechanisms, and the evaluation of efficacy is difficult in the pre-clinical investigation. Humanized mice with reconstructed human immune system are useful for drug discovery of molecular-targeted drugs related to the immune system, and evaluation of antibody production by vaccines. The development...